5. TCU vs. West Virginia (12)

Quarterback Kenny Hill leads his TCU Horned Frogs into Milan Puskar Stadium to challenge the crushing defense of the Mountaineers, who at 5-0, look to remain undefeated atop the Big 12. 

4. Ohio State (2) vs. Penn State

Urban Meyer’s undefeated Buckeyes head into an electric Beaver Stadium for a clash with long-time rivals Penn State, led by running back marvel Sequon Barkley.

3. Ole Miss (23) vs. LSU (25)

Quarterback Chad Kelly and the Ole Miss Rebels invade Tiger Stadium to face off against the SEC’s top defensive unit, led by LSU power lineman Arden Key.    

2. Arkansas (17) vs. Auburn (21)

The surging Auburn Tigers may be without star back Kerryon Johnson, in which case quarterback Sean White will have lead the attack against Bret Bielema’s ferocious Arkansas Razorbacks.

1. Texas A&M (6) vs. Alabama (1)

Quarterback Trevor Knight and the undefeated Aggies are headed for a spotlight showdown in Tuscaloosa as they face walking highlight reel Jalen Hurts and his top-ranked Crimson Tide